This is an international site for Exjade® (Deferasirox) and is intended for Health Care Professionals outside the U.S. The information on the site is not country-specific, and may contain information that is outside the approved indications in the country in which you are located. Please contact your local Novartis representative for the latest information specific to your country.

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In this section:

Extension Data

Long-term Serum Ferritin Reductions
Demonstrated in Sickle Cell Disease

Serum Ferritin Trends Decrease Over 6 Years1
Long-term Serum Ferritin Reductions

Study 109 was extended to further analyze the long-term efficacy and safety of EXJADE in patients with transfusion-dependent sickle cell disease.
Only 43 out of the original 132 patients entered the sixth year.1

EXJADE SAFETY
PROFILE ACROSS
ANEMIAS

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TRANSFUSION-DEPENDENT
β-THALASSEMIA
MYELODYSPLASTIC SYNDROMES SICKLE CELL DISEASE APLASTIC AND OTHER ANEMIAS TOOLS AND RESOURCES ALL ABOUT EXJADE

EXJADE is indicated for the treatment of chronic iron overload due to frequent blood transfusions (≥ 7 ml/kg/month of packed red blood cells) in patients with beta thalassemia major aged 6 years and older.

EXJADE is also indicated for the treatment of chronic iron overload due to blood transfusions when deferoxamine therapy is contraindicated or inadequate in the following patient groups:

  • in patients with beta thalassemia major with iron overload due to frequent blood transfusions (≥7 ml/kg/month of packed red blood cells) aged 2 to 5 years
  • in patients with beta thalassemia major with iron overload due to infrequent blood transfusions (<7 ml/kg/month of packed red blood cells) aged 2 years and older
  • in patients with other anemias aged 2 years and older