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Exjade Dosing & Administration

Optimize Therapy With Individualized Dosing

Escalation Dosages with EXJADE®

Titrate and monitor to reach chelation goals

  • The recommended initial daily dose of EXJADE is 20 mg/kg body weight
  • Monitor serum ferritin monthly and assess trends with steady-state levels
  • Titrate EXJADE by steps of 5 mg/kg/day to 10 mg/kg/day every 3 to 6 months based on individual patient′s response and therapeutic goals (maintenance or reduction of iron)
  • EXJADE is approved at doses up to 40 mg/kg/day for patients not adequately controlled with doses of 30 mg/kg (eg, serum ferritin levels persistently above 2,500 μg/L and not showing a decreasing trend over time)
  • Doses above 40 mg/kg are not recommended because there is only limited experience with doses above this level
  • Dose reductions, in steps of 5 to 10 mg/kg, should be considered in patients whose serum ferritin levels have reached the target (usually between 500 and 1000 μg/L) in order to maintain serum ferritin levels within the target range
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Titrate from the recommended starting dose of 20 mg/kg/day based on individual patient′s response and therapeutic goals.

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Learn more about how to properly administer once - daily oral EXJADE

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